BRIEF REPORT
A Case of Shingles Following Auricular
Acupuncture
Steven A. Kewish, MD
This is a case report of an occurrence of shingles (herpes zoster [HZ]) following auricular acu-
puncture. The patient developed acute reactivation HZ in the V1 distribution of the right trigeminal
nerve involving the forehead, scalp, and medial upper eyelid 13 days after being treated with au-
ricular acupuncture for chronic low-back pain. The lesions were initially painless, but they clus-
tered and became painful within 2 days. The patient was treated with oral valacyclovir 1000 mg, 3
times daily for 7 days, and ibuprofen as needed. The lesions resolved without sequelae.(J Am
Board Fam Med 2017;30:552–555.)
Keywords: Acupuncture Therapy, Herpes Zoster, Low Back Pain, Trigeminal Nerve, Valacyclovir
A 53-year-old male patient sought treatment for
chronic low-back pain through auricular acupunc-
ture. A standard “battlefield acupuncture” tech-
nique was applied to reduce pain (Figure 1). This
technique calls for the use of 5 semipermanent
needles applied to specific points on 1 or both ears.
The patient recalls the initial Aiguille Semi-Perma-
nente (ASP) needle, placed at the base of the right
intertragic notch (labeled “cingulate gyrus” in Fig-
ure 1), causing a shocklike sensation. Additional
ASP needles were placed bilaterally at the left cin-
gulate gyrus and at the midantitragus (labeled
“thalamus” in Figure 1). None of the subsequent
needles caused the same shocklike sensation. These
were the only ASP needles used, and they remained
in place for 48 hours, after which they became loose
and fell out. The treatment succeeded in relieving
the patient’s low-back pain for about 10 days. Ap-
proximately 12 days after the acupuncture session,
the patient reported that he began feeling mild
malaise, which he treated with rest. The following
morning he awoke and noticed an area of redness
just below the hairline on the right forehead. As the
day progressed the area became larger, and by the
end of the day, a small cluster of vesicles had ap-
peared. The next morning a second cluster devel-
oped, beginning above the hairline on the right and
extending down in a narrow broken line toward the
medial right eyebrow and terminating near the me-
dial canthus (Figure 2). Neither of these were ini-
tially painful but “tingling” was noted. The patient
visited his family physician, who diagnosed him
with shingles in the V1 distribution of the trigem-
inal nerve. The patient was subsequently evaluated
by an ophthalmologist, who found no ocular in-
volvement.
This patient had a history of chicken pox at age
10, no history of herpes zoster (HZ), and had never
received Zostavax or a varicella titer. A detailed
history and physical examination of this patient
revealed no significant acute or chronic medical
conditions, and no other issues predisposing to the
development of shingles.
Standard treatment for HZ was initiated with
valacyclovir, and symptoms were managed with
oral ibuprofen. The patient’s symptoms resolved
without complication and, at the time of this writ-
ing, had not returned.
Case Review
Acupuncture is frequently used for the treatment of
pain associated with shingles, but auricular acu-
This article was externally peer reviewed.
Submitted 15 February 2017; revised 18 February 2017;
accepted 21 February 2017.
From the Naval Hospital Bremerton, Bremerton, WA.
Current affiliation: NATO Role 3 Multinational Medical
Unit, Kandahar, Afghanistan.
Funding: none.
Conflict of interest: none declared.
Corresponding author: Steven A. Kewish, MD, Family
Medicine, 1 Boone Road, Bremerton, WA 98312 E-mail:
552 JABFM July–August 2017 Vol. 30 No. 4 http://www.jabfm.org
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puncture has not, to my knowledge, previously
been described as being associated with HZ reac-
tivation. Numerous other potential side effects are
known; however, only 1 primary source document
was located showing an association between acu-
puncture and herpes.
1–3
A literature review noted
several cases of trauma-induced trigeminal nerve
zoster, but none were specifically associated with
auricular acupuncture (Figures 1–3).
Discussion
After acute varicella zoster infection, the virus
migrates up sensory axons and becomes latent in
regional ganglia or nuclei, where it remains dor-
mant, often for years. Trigeminal nerve nuclei
and thoracic spinal ganglia are the most com-
monly affected. Under certain conditions, the
virus reactivates and travels to the dermatome
corresponding to its nucleus or ganglion, pro-
ducing the typical painful, vesicular rash of shin-
gles. Recurrence can happen at different ages and
in different locations in the same person. Typi-
cally, however, subsequent cases are progres-
sively less common. Precipitating factors for
shingles include stress, trauma, chronic disease,
systemic illness, and immune disorders, among
others.
2,3
Reactivation is also influenced by the
age-related waning of immunologic response by
the host to the virus, prompting the recommen-
dation for shingles vaccination. While Zostavax
is approved by the FDA for use in patients aged
50 years and older, the Centers for Disease Con-
trol and Prevention recommend routine vaccina-
tion starting at age 60, largely because of the
limited vaccine supply and a lower incidence of
postherpetic neuralgia among people in their 50s
(based on the Centers for Disease Control and
Prevention and Advisory Committee of Immuni-
zation Practices 2014 guidelines).
Acupuncture is a procedure that represents a
minor trauma. Physical trauma and surgical proce-
dures are known to precipitate HZ eruptions, in-
cluding in cranial nerve distributions.
4–7
A case-con
-
trol study in 2012 noted an increased proportion of
trauma in HZ cases compared with controls in any of
the 52 weeks before the onset of symptoms; the
greatest proportion occurred in the first week. In
addition, patients diagnosed with cranial HZ were
25 times as likely as controls to have had cranial
trauma during the week before HZ onset.
8
A case-
control study by Thomas et al
4
in 2004 concluded
that recent trauma was associated with an adjusted
12-fold increase in the risk of developing HZ at
the site of the trauma within 1 month. Mecha-
nisms by which trauma might reactivate the zos-
ter virus are not specifically known, but stimula-
Figure 1. Approximate needle insertion sites for
Battlefield Acupuncture.
Figure 2. Shingles in the V1 distribution of the
Trigeminal Nerve.
doi: 10.3122/jabfm.2017.04.170051 Shingles Following Auricular Acupuncture 553
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tion of nerve nuclei or ganglia is proposed. The
literature suggests that outbreaks are most likely
to occur within the first month after the insult.
Although cause and effect cannot be proven in
this case, the timing, mechanism, and proximity
to the acupuncture “trauma” are compelling. The
proposed explanation for triggering the onset of
reactivation HZ in this patient is stimulation of
the trigeminal nuclei, perhaps via a branch of the
auriculotemporal nerve, secondary to the acu-
puncture (Figure 3).
Recommendations
HZ is a painful disease process with potential for
significant morbidity. Auricular acupuncture is be-
coming more widely used in outpatient settings
because of its quick and easy application, effective-
ness, and presumed safety. In the military, battlefield
acupuncture describes a limited auricular acupuncture
technique used to treat pain, and this technique is
common
9
(Figure 1). The 2 most common compli
-
cations of acupuncture are pneumothorax and hepa-
titis. When counseling susceptible individuals, shin-
gles should be considered as an additional, yet less
common, risk of this procedure. Verbal screening for
a history of varicella or shingles, monitoring after
treatment, and perhaps applying prophylaxis for at-
risk populations should considered.
To see this article online, please go to: http://jabfm.org/content/
30/4/552.full.
References
1. Chang TW. Letter: activation of cutaneous herpes
by acupuncture. N Engl J Med 1974;290:1310.
2. Rampes H, James R. Complications of acupuncture.
Acupunct Med 1995;13:26–33.
3. White AA. Cumulative review of the range and in-
cidence of significant adverse events associated with
acupuncture. Acupunct Med 2004;22:122–33.
4. Thomas SL, Wheeler JG, Hall AJ. Case-control
study of the effect of mechanical trauma on the risk
of herpes zoster. BMJ 2004;328:439 40.
5. Mansour N, Kaliaperumal C, Choudhari KA. Facial
herpes zoster infection by surgical manipulation of
the trigeminal nerve during exploration of the pos-
terior fossa: a case report. J Med Case Rep 2009;3:
7813.
Figure 3. Anatomy of the Trigeminal Nerve.
554 JABFM July–August 2017 Vol. 30 No. 4 http://www.jabfm.org
copyright.
on 19 September 2024 by guest. Protected byhttp://www.jabfm.org/J Am Board Fam Med: first published as 10.3122/jabfm.2017.04.170051 on 18 July 2017. Downloaded from
6. Lin KC, Wang CC, Wang KY, Liao YC, Kuo JR.
Reactivation of herpes zoster along the trigeminal
nerve with intractable pain after facial trauma: a
case report and literature review. BMJ Case Rep
2009;2009:pii. DOI: 10.1136/bcr.07.2008.0525.
7. Foye PM, Stitik TP, Nadler SF, Chen BA. Study of
posttraumatic shingles as a work related injury. Am J
Ind Med 2000;38:108–11.
8. Zhang JX, Joesoef RM, Bialek S, Wang C, Harpaz R.
Association of physical trauma with risk of herpes
zoster among Medicare beneficiaries in the United
States. J Infect Dis 2013;207:1007–11.
9. Jonas WB, Welton RC, Delgado RE, Gordon S,
Zhang W. CAM in the United States military: too
little of a good thing? Med Care 2014;52(12 Suppl
5):S9–12.
doi: 10.3122/jabfm.2017.04.170051 Shingles Following Auricular Acupuncture 555
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